Adalimmab is a monoclonal antibody indicated for the treatment of rheumatoid arthritis, ankylosing spondylitis or Crohn disease, as it decreasing inflammation in the body, which occurs inflammatory diseases.
This remedy is found in the form of an injectable pen, filled syringe or vial, with humb, Hyrimoz or Hadlima trade names, sold by presenting a prescription.
Adalimmab should be used at doses and treatment time oriented by the doctor, according to the condition to be treated and the severity of the symptoms.
So that Serve
Adalimmab is indicated for the treatment of:
- Rheumatoid arthritis or psoriatic arthritis;
- Ankylosing spondylitis or severe axial spondylooarthritis;
- Crohn’s disease, ulcerative colitis or ulcerative retocolitis;
- Psoriose;
- Hidradenite Supurativa;
- Non -infectious uveitis.
In addition, adalimmab may be indicated for polyarticular juvenile idiopathic arthritis or entestitis -related arthritis.
The use of adalimmube should only be done with medical indication and individualized doses, according to the age and condition to be treated.
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Adalimmube is a monoclonal antibody that acts by binding to a specific protein, the tumor necrosis factor (TNF-alpha).
This protein is present at high levels in the body in inflammatory diseases that occur in joints, spine, intestines and skin, and thus helps to reduce inflammation and reduce symptoms.
Is there adalimmab in SUS?
Adalimmab 40 MG is offered free of charge by SUS, provided it has medical indication.
How to use
Adalimmab should be used through subcutaneous application, ie over the skin of the abdomen or thigh, inserting the needle to 45 degrees into the skin and injecting the liquid for 2 to 5 seconds. See how to apply subcutaneous injection correctly.
Adalimmab dosage
Adalimmab’s dosage varies according to the condition to be treated and age, which includes:
1. Her fucking 40 mg
The recommended doses of adalimmab 40 mg for adults, varies according to the condition to be treated, and includes:
Treatment time with adalimmab should be guided by the rheumatologist.
2. She still fed 20 mg
Adalimmab 20 mg is usually indicated as an initial treatment of polyarticular juvenile idiopathic arthritis or entestitis -related arthritis.
The recommended dose for children over 6 is:
- Polyarticular Juvenile Idiopathic Arthritis in children weighing from 10 to 30 kg: 1 adalimmab injection 20 mg every 14 days;
- Arthritis related to entry in children weighing from 15 to 30 kg: 1 adalimmab injection 20 mg every 14 days;
- Uveitis in children less than 30 kg: 1 Adalimmab Injection 20 mg every 14 days, associated with the use of methotrexate.
Adalimmab doses for children should always be oriented by the pediatrician and may be increased by the doctor after initial treatment.
Adalimmab 20 mg can also be indicated by the pediatrician as a maintenance dose for the treatment of ulcerative colitis or Crohn disease.
3. She still faded 80 mg
Adalimmab 80 mg injection may be indicated as an initial treatment of psoriasis in plates or uveitis in adults.
In addition, for children over 6, Adalimmab 80 MG can also be indicated as a dose for the initial treatment of Crohn disease or ulcerative colitis in children under 40 kg.
For suppurative hydradenitis in children over 12 years old who weigh between 30 and 60 kg, the doctor may also indicate Adalimmab 80 mg as an initial dose.
Care when using adalimmab
Some precautions are important in using adalimmab, such as:
- Remove Adalimmab from the refrigerator, about 15 to 30 minutes before its application so that it reaches the room temperature;
- Wash hands with water and mild soap before and after applying adalimmab;
- Pass the damp alcohol scarf, supplied on the packaging, on the skin where adalimmab will be applied;
- Alternate the place of application of adalimmab to each application, that is, do not apply at the same place where the last dose was taken.
In addition, the syringe, needle or injectable pen should be discarded after use and never reused.
Possible side effects
The most common side effects of adalimmab are headache or muscle pain, red spots on the skin, cough, asthma or infections.
Infection may also emerge in the respiratory tract, sinusitis, pneumonia, pharyngitis, nausea, vomiting, abdominal pain or mood swings, anxiety or insomnia.
In addition, conjunctivitis, vertigo, increased heart rate, high blood pressure, pain or bleeding at the injection site may arise.
Adalimmab can cause severe allergic reactions or anaphylaxis. In such cases, you should look for the nearest emergency room immediately. Learn to identify the symptoms of severe allergic reaction.
Who should not use
Adalimmab should not be used in the following situations:
- Children under 2;
- Immunosuppressed people;
- Active tuberculosis or other types of chronic infection;
- Moderate to severe heart failure;
- Allergy to any of the components of the formula.
During pregnancy or breastfeeding, adalimmab should only be used if recommended by the doctor after evaluating the benefits of treatment for women and possible risks to the baby.
In addition, during treatment with adalimmab it is not recommended to take alive or attenuated virus vaccines as it can cause serious infections. Thus, before taking any vaccine, you should consult the doctor responsible for the treatment.
Adalimmab should not be applied to regions of the skin with irritation, sensitivity, inflammation, wound or redness.
Source: www.tuasaude.com